Marine Resiliency Study


The Marine Resiliency Study (MRS) is a prospective study of factors predictive of posttraumatic stress disorder (PTSD) among approximately 4,000 Marines deployed to Iraq or Afghanistan.

Starting in 2008, we collected data at pre-deployment and multiple times after at after a 7-month deployment to combat zones in Iraq and Afghanistan.

Integrated with these data are medical and career histories from the Career History Archival Medical and Personnel System (CHAMPS) database.

Longitudinal psychological and behavioral assessments include psychiatric and medical clinical interviews, self-report questionnaires, and neuropsychological assessments. Biological measures assessed so far include biomarkers, hemodynamics, and psychophysiology.

Genomics data includes genome-wide genotype data, methylome, and transcriptome measures on a subset of samples. An extensive biobank storing blood, saliva, urine, and DNA/RNA will allow future assays.